Enye yezinto ezintsha ezisetshenzisiwe ze- HTC One isikhombimsebenzisi esisha se-HTC Sense 5, isikhumba esigijima ngaphezulu kwe-Android futhi esinikeza ezinye izinto ezintsha njengeBlinkfeed, ekhombisa uchungechunge lwamabhulokhi anezindaba eziphezulu, imininingwane kanye nokuphakelwa kwemidiya yezokuxhumana.
Ngenhlanhla (noma cha), i-HTC iqinisekisile ukuthi amanye ama-Smartphones ayo azothola isibuyekezo namuhla futhi angathembela kusixhumi esibonakalayo esisha, kufaka phakathi i-HTC One X One X +, S ne-Butterfly, kanye nokuhlukahluka kwawo kwamanye amazwe.
Le nkampani ayikakuqinisekisi ukuthi lokhu kuzokwenzeka nini, kodwa yathi kuzoba "ezinyangeni ezimbalwa ezizayo." Kodwa-ke ezinye izici ezenzelwe i-hardware enamandla ye-HTC One ngeke zitholakale kuwo wonke amadivayisi, mhlawumbe zibhekise kwezinye izici zekhamera.